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AI-Edigene? EGFR p.H773-V774insAH Reference Standard Plus

CBP10626

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產品描述
產品數據庫
Introduction 
Format Genomic DNA
Description EGFR (HER1), epidermal growth factor receptor, is a tyrosine kinase receptor, which activates RAS/RAF/MEK and PI3K/AKT/mTOR pathways, leading to increased cell proliferation and growth. EGFR activating mutations, amplification, and overexpression are found in a variety of tumors, including non-small cell lung cancer and colorectal cancer, and the EGFRvIII variant is commonly found in glioblastoma.
   
Technical Data 
DNA Change: c.2315_2320dupCCCACG
AA Change p.H773-V774insAH
Mutation type Insertion - In frame
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_005228.5
Cosmic ID COSM1238028
Chr position(GRCh37) chr7-55249023--CCCACG (6bp)(EGFR:p.H773_V774insAH)
Buffer: Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purity Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

 

 

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