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首頁(yè) /診斷試劑 /用藥指導(dǎo)標(biāo)準(zhǔn)品 /他莫昔芬CYP2D6多態(tài)性 /CYP2D6*2_p.S486T Reference Standard

CYP2D6*2_p.S486T Reference Standard

CBPA0001

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產(chǎn)品描述
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Introduction  
Format Genomic DNA
Description CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.
   
Technical Data 
Gene CYP2D6
AA Change p.S486T
DNA Change NM_000106.6_c.1457G>C
Chr position (GRCh38) NC_000022.11_g.42126611C>G
Allelic Frequency 100%
Zygosity Homozygous
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8°C
Expiry 36 months from the date of manufacture

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